The effects of moringa seed supplements on oxidative stress and 10 km running performance

Main Article Content

Nasser Abouzeid
https://orcid.org/0000-0002-1484-4197
Mohamed Saad
Bogdan-Constantin Ungurean
https://orcid.org/0000-0001-9596-2162
Alin Larion
https://orcid.org/0000-0001-6419-5095
Adam Zajac
Walaa Kobacy
https://orcid.org/0009-0000-8259-679X
Usama Elgazzar
Gehad Mahmoud
Hachim Shani
Hatem Ibadi
Amr Hamza
https://orcid.org/0009-0004-1149-3792

Abstract

Athletes use herbal supplementation to increase physical fitness, reduce the potentially negative consequences of strenuous training, and gain a competitive edge. The goal of this study was to identify the effects of Moringa seed supplements on oxidative stress and 10 km running time. A double-blind, placebo-controlled clinical trial was conducted with 26 male runners. The participants were randomly divided into two groups: the experimental (supplemented) group (n = 15), which received 3% of the athlete’s body weight of moringa seed powder added to juices (orang without sugar 300 ml) in the evening after the training, three days a week for 8 weeks. The control (placebo) group (n = 11) received a placebo (orang without sugar 300 ml) at the corresponding times. After the intervention period, malondialdehyde levels were significantly reduced and 10 km running time was improved in the experimental group. No significant changes were observed in catalase, superoxide dismutase and glutathione concentrations in the two groups. In conclusion, moringa seeds were effective in enhancing endurance performance and reducing oxidative stress in a group of young endurance athletes.

Downloads

Download data is not yet available.

Article Details

Section

Sport Medicine, Nutrition & Health

Author Biographies

Nasser Abouzeid, Helwan University & King Faisal University

Department of Games Sports and Racquet Games Training. College of Physical Education for Boys. Helwan University.

Department of Physical Education. College of Education. King Faisal University.

Mohamed Saad, Benha University

Faculty of Sport Sciences.

Bogdan-Constantin Ungurean, Alexandru Ioan Cuza University of Iasi

Faculty of Physical Education and Sports.

Alin Larion, Ovidius University of Constanta

Faculty of Physical Education and Sports.

Walaa Kobacy, Sohag University

Faculty of Agriculture.

Usama Elgazzar, Alazhar University & Mansoura University

Faculty of Medicine. Alazhar University.

Faculty of Physical Education. Mansoura University.

Gehad Mahmoud, Qassim University

Department of Physical Education and Movement Science. Faculty of Education.

Hachim Shani, Almaaqal University

Faculty of Physical Education and Sports Science.

Hatem Ibadi, Almaaqal University

Faculty of Physical Education and Sports Science.

Amr Hamza, Sohag University

Faculty of Sport Sciences.

How to Cite

Abouzeid, N. ., Saad, M., Ungurean, B.-C., Larion, A., Zajac, A., Kobacy, W., Elgazzar, U., Mahmoud, G., Shani, H., Ibadi, H., & Hamza, A. (2025). The effects of moringa seed supplements on oxidative stress and 10 km running performance. Journal of Human Sport and Exercise , 20(3), 1012-1019. https://doi.org/10.55860/qy007e49

Funding data

References

Adebayo I.A., Arsad H., Samian M.R. Antiproliferative effect on breast cancer (MCF7) of Moringa oleifera seed extracts. (2017). Afr. J. Tradit. Complement. Altern. Med.; 14:282-287. https://doi.org/10.21010/ajtcam.v14i2.30

Araneda O.F., Urbina-Stagno R., Tuesta M., Haichelis D., Alvear M., Salazar M.P., García C. (2014). Increase of pro-oxidants with no evidence of lipid peroxidation in exhaled breath condensate after a 10-km race in non-athletes, J. Physiol. Biochem.; 70:107-115. https://doi.org/10.1007/s13105-013-0285-0

Bonoy Lamou, Germain Sotoing Taiwe, André Hamadou, Abene, Justin Houlray, Mahamat Mey Atour, Paul Vernyuy Tan. (2016). Antioxidant and Antifatigue Properties of the Aqueous Extract of Moringa oleifera in Rats Subjected to Forced Swimming Endurance Test, Oxid Med Cell Longev.:2016:3517824. https://doi.org/10.1155/2016/3517824

Cevallos-casals, B.A. and Cisneros-Zevallos, L. (2010). Impact of germination on phenolic content and antioxidant activity of 13 edibile seed species Food Chem.; 119(4): 1485-1490. https://doi.org/10.1016/j.foodchem.2009.09.030

Chinma, C.E.; Adewuyi, A.O. and Abu, J.O. (2009). Effect of germination on the chemical, functional and pasting properties of flour from brown and yellow varieties of tigernut. Food Res. Int.; 42(8). https://doi.org/10.1016/j.foodres.2009.04.024

Frederick S. Owens, Oluwabunmi Dada, John W. Cyrus, Oreoluwa O. Adedoyin, Georges Adunlin. (2020). The effects of Moringa oleifera on blood glucose levels: A scoping review of the literature, Complementary Therapies in Medicine, Volume 50, 102362. https://doi.org/10.1016/j.ctim.2020.102362

Ganguly R., Hazra R., Ray K., Guha D. (2005). Effect of Moringa oleifera in experimental model of Alzheimer's disease: Role of antioxidants. Ann. Neurosci.; 12:36-39. https://doi.org/10.5214/ans.0972.7531.2005.12030

Gehan Elsawy, Osama Abdelrahman, Amr Hamza. (2014). Effect of Choline Supplementation on Rapid Weight Loss and Biochemical Variables Among Female Taekwondo and Judo Athletes, Journal of Human Kinetics; 40(1):77-82. https://doi.org/10.2478/hukin-2014-0009

Giacoipo S., Rajan T.S., De Nicola G.R., Iori R., Rollin P., Bramanti P., Mazzon E. (2017). The Isothiocyanate Isolated from Moringa oleifera Shows Potent Anti-Inflammatory Activity in the Treatment of Murine Subacute Parkinson's Disease. Rejuvenation Res.; 20:50-63. https://doi.org/10.1089/rej.2016.1828

Hamidie Ronald Danie Ray, Calvin Chandra, Reza Pratama, Muhammad Naufal Abdurahman, Ronny Lesmana. (2023). The Potentiality of Moringa Oleifera to Increase Human Performance, International Journal of Human Movement and Sports Sciences 11(1): 58-64. https://doi.org/10.13189/saj.2023.110107

Haskell W.L. Kiernan M. (2000). Methodologic issues in measuring physical activity and physical fitness when evaluating the role of dietary supplements for physically active people, Am J Clin Nutr.; 72: 541S-550S. https://doi.org/10.1093/ajcn/72.2.541S

Karina Vargas-Sánchez, Edwin Garay-Jaramillo, and Rodrigo E. González-Reyes. (2019). Effects of Moringa oleifera on Glycaemia and Insulin Levels: A Review of Animal and Human Studies, Nutrients. 11(12): 2907. https://doi.org/10.3390/nu11122907

Kelvin J. A. Davies. (2016). The Oxygen Paradox, Oxidative Stress, and Ageing, Arch Biochem Biophys.; 595: 28-32. https://doi.org/10.1016/j.abb.2015.11.015

Marcela Vergara-Jimenez, Manal Mused Almatrafi, and Maria Luz Fernandez. (2017). Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease, Antioxidants (Basel). 6(4): 91. https://doi.org/10.3390/antiox6040091

Mohamed Soliman, Saad Hommod, Essam Hassan, Adil Aldhahrani, Adel Alkhedaide, Fayez Althobaiti, and Wafaa Abdou. (2020). Protective Impacts of Moringa oleifera Leaf Extract against Methotrexate-Induced Oxidative Stress and Apoptosis on Mouse Spleen, Evidence-Based Complementary and Alternative Medicine Volume 2020. https://doi.org/10.1155/2020/6738474

Piyush Kashyap, Shiv Kumar, Singh Riar, Charanjit Singh Riar, Navdeep Jindal, Poonam Baniwal, Raquel P. F. Guiné, Paula M. R. Correia, Rahul Mehra and Harish Kumar. (2022). Recent Advances in Drumstick (Moringa oleifera) Leaves Bioactive Compounds: Composition, Health Benefits, Bioaccessibility, and Dietary Applications, Antioxidants. 11(2), 402. https://doi.org/10.3390/antiox11020402

Ponce-Gonzalez, J. G., Corral-Pérez, J., Villarreal, E. S. D., Gutierrez-Manzanedo, J. V., Castro-Maqueda, G. D., Casals, C. (2021). Antioxidants Markers of Professional Soccer Players During the Season and their Relationship with Competitive Performance. Journal of Human Kinetics, 80, 113-123. https://doi.org/10.2478/hukin-2021-0089

Randriamboavonjy J.I., Rio M., Pacaud P., Loirand G., Tesse A. (2017). Moringa oleifera seeds attenuate vascular oxidative and nitrosative stresses in spontaneously hypertensive rats. Oxid. Med. Cell. Longev.; 4129459. https://doi.org/10.1155/2017/4129459

Romano-Ely B. C, Kent T. M, Saunders M. J, St Laurent T. (2006). Effect of an isocaloric carbohydrate-protein-antioxidant drink on cycling performance. Medicine and Science in Sports and Exercise; 38:1608-1616. https://doi.org/10.1249/01.mss.0000229458.11452.e9

Santos-Silva A, Rebelo M. I, Molnar E. et al. (2001). Leukocyte activation, erythrocyte damage, lipid profile and oxidative stress imposed by high competition physical exercise in adolescents. Clinica Chimica Acta. 306:119-126. https://doi.org/10.1016/S0009-8981(01)00406-5

Seifried H. E, Anderson D. E, Fisher E. I, Milner J. A. (2007). A review of the interaction among dietary antioxidants and reactive oxygen species. The Journal of Nutritional Biochemistry. 18:567-579. https://doi.org/10.1016/j.jnutbio.2006.10.007

Sen C. K. (2001). Antioxidants in exercise nutrition. Sports Medicine. 31:891-908. https://doi.org/10.2165/00007256-200131130-00001

Veronica Turcu, Pascal Wild, Maud Hemmendinger, Jean-Jacques Sauvain, Enrico Bergamaschi, Nancy B. Hopf, and Irina Guseva Canu. (2022). Towards Reference Values for Malondialdehyde on Exhaled Breath Condensate: A Systematic Literature Review and Meta-Analysis, Toxics. 10(5): 258. https://doi.org/10.3390/toxics10050258

Wafa W. M., El-Nagar H. A.; Gabr A. A.; Rezk M. M. (2017). Impact of Dietary Moringa Oleifera Leaves Supplementation on Semen Characteristics, Oxidative Stress, Physiological Response and Blood Parameters of Heat Stressed Buffalo Bulls, Journal of Animal and Poultry Production, Volume 8, Issue 9, Page 367-379. https://doi.org/10.21608/jappmu.2017.46008

Woranan Kirisattayakul, Jintanaporn Wattanathorn, Terdthai Tong-Un, Supaporn Muchimapura, Panakaporn Wannanon, and Jinatta Jittiwat. (2013). Cerebroprotective Effect of Moringa oleifera against Focal Ischemic Stroke Induced by Middle Cerebral Artery Occlusion, Oxidative Medicine and Cellular Longevity. https://doi.org/10.1155/2013/951415

Similar Articles

You may also start an advanced similarity search for this article.